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Rogue Pet Science


Origins Canine 5-in-1


For Dog Nutrition, Gut Health & Performance

  • Gives your dog a vibrant & shiny coat
  • Eliminates itchy skin
  • Provides natural relief for dogs with allergies
  • Adds essential joint support
  • Contains omega 3 & 6 plus pre-biotics, probiotics & digestive enzymes to improve gut health


  • UNIQUE FORMULA: Our canine probiotics, prebiotics, and digestive enzymes for dogs supplement powder utilizes wild caught fish protein and oil unaltered. This sets us apart from other dog vitamins and supplements with 10% wild fish oil in every serving.
  • 5 in 1 HEALTH BENEFITS: Unlike other dog supplements, our dog nutritional  supplements address your pets needs. Dog supplements for skin and coat care, anti-itching, digestion, gut health, and of course canine hip and joint. Origins multivitamin supplement does it all!
  • EASY TO USE WITH ALL AGE PETS: No more shoving pills down your best friends throat! Now enjoy the ease of sprinkling our dog probiotics powder on their favorite meal. They won't taste the difference, but they will feel the health benefits! Whether it's used as a senior dog supplement or a puppy probiotics supplement - our powder works great on their dry and wet food alike.
  • 100% MADE IN THE U.S.A.: Origins for dogs is a probiotic, prebiotic, and postbiotic powder for canines sourced domestically and we're proud of it. All the services and companies we work with to both run and grow our business are in Texas. Our militant effort to keep money in Texas and on main street allows us to impact more than pet health.

Package Includes:

  •  One (1) Rogue Pet Science | Origins 5-in-1 Dog Powdered Supplement | Includes Vitamins, Minerals, Fish Oils and More to Support Canine Hips, Joints, Skin & Coat, Allergies, and Gut Health 


Whole wild menhaden fish, Digestive enzymes, Probiotics, Pre-biotics, Yeast support, GI tract lining support

Directions for Use

  • How to Feed: Start slow. Use small amounts over 4 days to ease your dog into the full amount. 
  • Always Start Slow: We recommend adding water to Origins Canine 5in1 and stir contents with primary food until well-blended. Additional water can be added for desired consistency. 
  • Pregnant & Nursing: Adult dogs can be fed the amount suggested or more as needed to maintain good nutrition
  • Puppies: See our feeding chart for puppies and young dogs in the FAQ section below


Rogue made Origins Canine 5in1 to address the lack of quality and benefits of products on the market.

Origins Canine 5in1 Supplement for Dogs is 100% Honest & 100% Functional
Origins Canine 5 in 1 only adds to your efforts of nutrition and health and never subtracts.

Pre-biotic • Probiotic • Digestives Enzymes • Butyric Fatty Acid


Origins Canine 5 in 1 Nutrition Facts:

  • Our wild fish ingredients are better than regular commercial dog food & equal to raw in digestibility. Commercial dog foods can be difficult for your dog to digest for their full nutritional needs
  • Origins is full of nutrients! Wild fish protein and wild complete fish oil is full of nutrients for your dog, so we use the whole fish to add essential nutritional elements to your dog’s diet
  • Our product line offers sustainability, traceability, and digestibility
  • The only way to impact the system is to address the total gut health system

Origins is used as a food topper to improve the health, performance and nutrition in dogs. 

The benefits of Origins Canine 5in1 include:

  • Improved gut health with Omega 3 & 6 plus pre-biotics, probiotics & digestive enzymes 
  • Joint support and reduced inflammation
  • Vibrant & shiny coat
  • Reduces itchy skin and hot spots
  • Enhanced digestion

Origins Canine 5 in 1 Ingredients:

  • Whole wild menhaden fish
  • Digestive enzymes
  • Probiotics
  • Pre-biotics
  • Yeast support
  • GI tract lining support

When starting on Origins gradually add more daily until you reach the recommended daily amount.  The recommended amounts by weight are show in the images.  Add the recommended amount and mix in the food with water.  

Proximate Testing

The idea of optimal performance relying on optimal nutrition is very well established. The causal link of how our nutrition with gut health support can positively impact biomarkers of health and be the drivers of meaningful performance increases is where we set ourselves apart.

  • Probiotics and prebiotics modulate secretion of glucagon, oxyntomodulin, GLP-1 and GLP-2 gut hormones by the enteroendocrine cells
  • The gut microbiome affects every aspects of human and animal health. Probiotics and pre-biotics modulate the gut microbiome. Gut microbiome and gut hormones impact the health of its host by mediating the dietary metabolism, gut permeability and nutrient absorption.
  • Studies have speculated that the role of the gut microbiome influences the production of gut hormones. Insulin and Glucagon works together for the control of cellular homeostasis. Impairment of this homeostasis results in diabetes, obesity and cardiovascular diseases.
  • Until now, the influence of probiotics and pre-biotics on the secretion of gut hormones such as glucagon-like peptide-1(GLP-1), glucagon-like peptide -2 (GLP-2), oxyntomodulin and glucagon were not understood clearly.
  • In this study, we have evaluated the effect of probiotic and pre-biotic supplements on the gut hormones levels in canine models. Dogs have been used as a translational model for diabetes mellitus diagnostics and therapeutics. The gut microbiome of dogs is closer to humans than pigs or mice. Probiotic and pre-biotic interventions have been proposed for the treatment of diabetes and obesity and metabolic syndromes.
  • Ansh Labs, USA, has developed specific immunoassays (ELISA) for canine glucagon family hormones. Glucagon, a 29-amino acid peptide secreted from pancreatic alpha cells in response to hypoglycemia. Glucagon is derived from proteolytic cleavage of proglucagon molecule by PC2 enzyme in pancreas.
    Furthermore, Glucagon, Glicentin, oxyntomodulin, GLP-1 and GLP-2 are produced by PC1/3 enzyme in intestine and brain. In this study, 10 male and female dogs from different ages and breeds were given probiotic and pre-biotic supplementation for one month.
  • Plasma samples were collected after 8 hrs. of fasting at before and after study period of one month. The plasma samples were measured for the circulating levels of glucagon, oxyntomodulin, GLP-1, and GLP-2 before and after supplementation.
    After pre-biotics and probiotics intervention for 4 weeks, the mean fasting levels of oxyntomodulin and GLP-1 were significantly changed. The mean value of oxyntomodulin decreased and the mean value of GLP-1 increased significantly after intervention. The mean value of glucagon and GLP-2 were not altered significantly.
  • The results suggest that pro and pre-biotic dietary supplements significantly alter the secretion of gut hormones by enteroendocrine cells. These alterations of gut hormone secretions may underlie some of the physiological effects of probiotic and pre-biotic interventions in patients with metabolic of intestinal dysfunctions. For example, the basal levels of glucagon and oxyntomodulin were higher in diabetes and obesity patients than normal controls in human studies. GLP-2 levels were higher in patients with Inflammatory bowel disease which increases the gut permeability. GLP-1 receptor analogues has been used for the treatment for diabetes. We suggest that these gut hormones may serve as biomarkers for the evaluation of efficacy of pre-biotics and probiotics.

3 Sizes Available:  1/2 lb., 2 lb. & 5 lb.

Availability:  Usually ships in 7-14 business days.


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